Experiment of Blood-Activating and Stasis-Eliminating Effects of Wuling Capsule in Rats

Aim To observe blood-activating and stasis-eliminating effects of Wuling capsule in rats.Methods The model of blood stagnation was established by giving rats high dose of adrenaline and immersing them into freezing water.The indexes of hemorheology were detected by Rheogoniometer.Prothrombin(PT),Partial thromboplastin time(APTT) and fibrinogen(FIB) were measured by auto-appratus of blood viscocity.Results Wuling capsules could decrease high rate of shear of whole blood viscosity, middle rate of shear of whole blood viscosity,low rate of shear of whole blood viscosity,high rate of shear of the whole blood reduction viscosity,high rate of shear of whole blood relative viscosity and low rate of shear of whole blood relative viscosity markedly while had no effects on plasma viscosity.It could also increase RBC inflexibility and packed cell volume and elongate APTT(P0.01,P0.05).Wuling capsules could recover the whole blood viscosity,RBC inflexibility and packed cell volume,which made no significant difference compared to Fufangdanshen guttae.Conclusion Wuling capsule can promote blood circulation by removing blood stasis.