Effect of Rushu on Improving Auricle Microcirculation in Mice and the Hemorheology in Acute Blood-stasis Model Rats

Objective: To investigate the effects of Rushu on improuing auricle microcirculation in mice and the hemorheology in acute blood-stasis model rats,to describe the correlation in treatment to hyperplasia of mammary gland between TCM and western medicine and to provide doctors with scientific references for administration in clinic.Method:To evaluate the effects of Rushu on improving auricle microcirculation disturbance model in mice induced by adrenalin and the hemorheology in acute blood-stasis model rats induced by adrenalin and ice water stimulation.Result:The diameter of micro-arteriole and micro-vein could be increased in all of three groups given Rushu at the dosages of 7g/kg,14g/kg and 28g/kg,and Showed significant changes compared with normal group(P0.05,0.01).Groups given Rushu at dosages of 3.5g/kg,7g/kg and 14g/kg were decreased significantly the viscosity of the whole blood,the whole blood reduced at low sharp rate and plasma compared with control group(P0.05,0.01).Conclusion Rushu can increase the diameter of capillary,decrease the viscosity of blood,and improve microcirculation and hemorheology.