Correlation study between atherosclerosis degree of left anterior descending coronary artery and changes of left ventricular function based on 64-slice CT

Objective:To evaluate the correlation between the left anterior descending coronary artery(LADCA) atherosclerosis and changes of cardiac function by 64-slice spiral CT.Methods:83 cases with LADCA atherosclerotic stenosis diagnosed by 64-slice CT and 20 normal cases as control group were studied.All of them underwent 64-slice CT coronary angiography.The parameters including left ventricular myocardial mass(LVMM),left ventricular ejection fraction(LVEF),left ventricular end diastolic volume(LVEDV),left ventricular end systolic volume(LVESV),left ventricular single-shot volume(LVSV),were calculated.All of the subjects studied were divided into 3 groups according to the degree of stenosis of LADCA(50%,50%~75%,75%),and the results were analyzed statistically.Results:There were no significant changes of cardiac function in the 21 cases of group A(luminal stenosis 50%).In the 33 cases of group B(luminal stenosis 50%~75%),the main changes were increase of LVMM and LVESV,with decrease of LVEF.In the 29 cases of group C(luminal stenosis 75%),multiple soft plaque/mixed plaques could be assessed,the function of left ventricle was obviously reduced.Conclusion:With increasing of the LADCA stenosis,the cardiac function underwent changes from compensation to dysfunction in a dynamic process.64-slice spiral CT provide an important role in the evaluation of the degree of coronary artery stenosis and the correlation with cardiac function.