The study on the correlation between hs-CRP and the risk factors of cerebral infarction

Objective To investigate the relationship between the hs-CRP and the risk factors of cerebral infarction.Methods The levels of serum hs-CRP,blood pressure,blood sugar(GLU),blood lipid,NO,ET,etc.were measured and the ultrasound of bilateral carotid arteries was examined in 116 patients with acute cerebral infarction(infarction group),34 patients(control A) who had risk factors of cerebral infarction,but had not developed cerebral infarction and 32 healthy subjects(control B).The relationship between concentration of hs-CRP and the risk factors of cerebral infarction was analyzed.Results From the linear correlation and regression analysis results,the level of the hs-CRP was positively correlated with the age,the history of diabetes,fibrinogen(FIB),ET,WBC count and intima-media thickness of carotid artery(IMT),and negatively correlated with the level of NO(P0.05).Cerebral infarction,FIB,ET,WBC,IMT,GLU and blood viscosity were the main factors influencing hs-CRP.Conclusions hs-CRP is related with the risk factors of cerebral infarction.hs-CRP is involved in the occurrence and progress of acute cerebral infarction through the risk factors of cerebral infarction.Therefore,hs-CRP may play an important role in the prevention and treatment of cerebral infarction.