Correlative Analysis of serum high sensitivity C-reactive protein levels in patients with cerebral infarction

Objective To observe the changes of serum high sensitivity C-reactive protein(hs-CRP) levels in patients with cerebral infarction in order to investigate the relationships between the levels of hs-CRP and pathogenetic condition of cerebral infarction.Methods The serum levels of hs-CRP were measured in 148 patients with cerebral infarction and 80 healthy people,and the correlation with the scale of clinical neurologic deficit were analyzed.Results The levels of serum hs-CRP in patients with cerebral infarction were significantly higher than that in healthy controls(P0.01).There was a significant difference among different clinical subtype groups of cerebral infarction(P0.01).There was a significant positive correlation between the level of hs-CRP and the scale of clinical neurologic deficit in patients with cerebral infarction(r=0.618,P0.01).Conclusion The high levels of serum hs-CRP are highly associated with the occurrence of cerebral infarction,and the level of hs-CRP may reflect the degree of cerebral infarction.