Study of relationship between serum high sensitive C-reactive protein and acute cerebral infarction

Objective To investigate relationship between the level of serum high sensitive C-reactive protein (hs-CRP) and severity extent,risk factors of acute cerebral infarction. Methods The serum hs-CRP was measured in 186 patients with atherothrobotic cerebral infarction(ACI), in 155 patients with lacunar infarction (LI) and in 329 normal controls by automatic analyzer, levels of blood glucose and blood lipid were detected at the same time. The relationship between hs-CRP and the degree of nerve damage in patients with acute cerebral infarction observed and analyzed. Results The levels of hs-CRP in patients with ACI and LI were higher significantly than that in the normal controls(all P0.05).There was correlation between the level of hs-CRP and the degree of nerve damage in patients with acute cerebral infarction ( P0.05).There were correlations between the the levels of hs-CRP and age, diastolic blood pressure, the levels of blood glucose and triglyceride in ACI patients (r=0.261,0.222,0.261,0.166,all P0.05).There were correlations between the hs-CRP and age, systolic blood pressure, the level of blood glucose, cholesterol and high density lipoprotein in LI patients(r=0.294,0.456,0.245,0.402, -0.371,all P0.05). Conclusions There is a relationship between the level of hs-CRP and severity extent of acute cerebral infarction. The level of serum hs-CRP may be correlated with the risk factors of acute cerebral infarction.