1996•Zhongguo yaolixue tongbaoRequires access
Effects of neferine on blood pressure, platelet aggregation and thrombus formation in rats
Hu Wen
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Abstract
Effects of neferine on blood pressure, platelet aggregation and thrombus formation in rats were studied by turbidimetry. The results showed that neferine dose dependently inhibited platelet aggregation induced by ADP and collagen in normal rats, renal hypertensive rats and high fat fed rats at the same time when it decreased blood pressure and markedly lengthened occlusive thrombus formation time by electric stimulation. It was suggested that neferine had effects of decreasing blood pressure as well as antiaggregation and antithrombosis.