Surveillance of Bacterial Resistance among E.coli and Klebsiella Pneumoniae in Guangzhou from 1998 to 2003

Objective:To investigate the resistance of E.coli and Klebsiella pneumoniae in Guangzhou from 1998 to 2003.Methods:1646 strains E.coli and 1175 strains Klebsiella pneumoniae from 12 hospitals were tested by Kirby-Bauer method.Results:A strain E.coli was resistant to imipenem;The resistant rates of 1646 strains E.coli were as follows:piperacillin/tazoba 6.2%,ceftazidime 6.6%,cefoperazone/sulbac 8.4%,amikacin 8.3%.The resistant rates of 1175 strains Klebsiella pneumoniae to cefepime was 9.8%,cefoperazone/sulbac 9.3%.The resistant rate to ciprofloxacin:E.coli was 68.6% and Klebsiella pneumoniae was 32.8%.The resistant rate to amikacin and ceftazidime of Klebsiella pneumoniae were higher than E.coli.Conclusion:In vitro activities of most tested antimicrobial agents to E.coli and Klebsiella pneumoniae are steady from 1998 to 2003.Continual surveillance studies will be essential.