Distribution of common pathogens from children with urinary tract infection and antimicrobial resistance

OBJECTIVE To approach the distribution and antimicrobial resistance of pathogenic bacteria in urinary tract infecion in children,to provide the evidence of anti-infection treatment for the clinician.METHODS The strains isolates from urine specimen from Jan.2006 to Dec.2009 were included in this study.The positive results of urine culture were analyzed statistically.Referring to National Guide to Clinical Laboratory Procedures,the strains were cultured and identified.The susceptibility testing was performed by disc diffusion method.The resistance results were assessed according to CLSI 2006-2009 breakpoints.RESULTS The detection rate of the pathogens was 16.2%.The majority was Escherichia coli which accounted for 36.3%.Except for E.coli and Klebsiella peumoniae were 100.0% sensitive to carbapenems to and Enterococci were 100.0% sensitive to glycopeptides,the pathogenic bacteria in children with urinary tract infection were highly resistant to the most of the commonly used antibiotics.CONCLUSION The drug resistance of the pathogens causing urinary tract infection keeps an increasing tendency,which is closely related to the clinical abuse of broad spectrum antibiotics.