2002•The Journal of Pharmaceutical PracticeRequires access

Determination of content of phenol in ear-drops by differential spectrophotometry

Ke Zhan

Abstract

OBJECTIVE:To establish differential spectrophotometry method for determining phenol and to eliminate interference of excipient.METHODS:Determining ΔA different ultraviolet spectrum of phenol in 0.1mol·L -1 NaOH and water,detection wave length 288nm.RESULTS:The recovery was 99.8%, RSD =0 12%.CONCLUSION:The method is simple and accurate.

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Key concepts: Phenol, Spectrophotometry, Chemistry, Interference (communication), Differential (mechanical device), Chromatography, Excipient, Computer science