2005Strait Pharmaceutical JournalRequires access

Content Determination of Phenol Ear Drops by Ultravoilet Spectrophotometry

Shao Li-xiao

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Abstract

OBJECTIVE To establish a method for the determination of phenol in phenol ear drops.METHODS Ultravoilet spectrophotometry was used to determine the content of phenol at wavelength 270nm.RESULTS The content of phenol in phenol ear drops presented a good linear relationship over the range of 10~30mg·L~(-1)(r=0.9997).The average recovery was 99.7%,RSD 0.76%(n=5).CONCLUSION This method used in this study is simple,accurate,stable and can be reliable for the quality control of phenol ear drops.

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OBJECTIVE To establish a method for the determination of phenol in phenol ear drops.METHODS Ultravoilet spectrophotometry was used to determine the content of phenol at wavelength 270nm.RESULTS The content of phenol in phenol ear drops presented a good linear relationship over the range of 10~30mg·L~(-1)(r=0.9997).The average recovery was 99.7%,RSD 0.76%(n=5).CONCLUSION This method used in this study is simple,accurate,stable and can be reliable for the quality control of phenol ear drops.

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Available abstract

OBJECTIVE To establish a method for the determination of phenol in phenol ear drops.METHODS Ultravoilet spectrophotometry was used to determine the content of phenol at wavelength 270nm.RESULTS The content of phenol in phenol ear drops presented a good linear relationship over the range of 10~30mg·L~(-1)(r=0.9997).The average recovery was 99.7%,RSD 0.76%(n=5).CONCLUSION This method used in this study is simple,accurate,stable and can be reliable for the quality control of phenol ear drops.

Key concepts: Phenol, Spectrophotometry, Chemistry, Linear relationship, Chromatography, Linear range, Mathematics, Detection limit

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