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The significance of urinary Malb/Cr ratio in diagnosis of early diabetic nephropathy

Liu Ming-kai

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Abstract

Objective To study the significance of urinary Malb/Cr ratio in diagnosis of early diabetic nephropathy.Methods The levels of urinary microablumin and creatinine were determined by Hitachi-7180 fully automatic biochemical analyzer in 124 patients with typeⅡ diabetes mellitus and 58 healthy controls.Results The logarithm of urinary Malb/Cr in diabetes group was significantly higher than that of healthy group(P0.001).The logarithm of urinary Malb/Cr was not correlated with blood level of glucose(r=0.001) in diabetic nephropathy,and it was related with amount of 24 hours urinary protein(r=0.403).Conclusion The increase in urinary Malb/Cr indicates the early renal damage in diabetes patients,and it has great significance in diagnosis of early diabetic nephropathy.

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Objective To study the significance of urinary Malb/Cr ratio in diagnosis of early diabetic nephropathy.Methods The levels of urinary microablumin and creatinine were determined by Hitachi-7180 fully automatic biochemical analyzer in 124 patients with typeⅡ diabetes mellitus and 58 healthy controls.Results The logarithm of urinary Malb/Cr in diabetes group was significantly higher than that of healthy group(P0.001).The logarithm of urinary Malb/Cr was not correlated with blood level of glucose(r=0.001) in diabetic nephropathy,and it was related with amount of 24 hours urinary protein(r=0.403).Conclusion The increase in urinary Malb/Cr indicates the early renal damage in diabetes patients,and it has great significance in diagnosis of early diabetic nephropathy.

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Available abstract

Objective To study the significance of urinary Malb/Cr ratio in diagnosis of early diabetic nephropathy.Methods The levels of urinary microablumin and creatinine were determined by Hitachi-7180 fully automatic biochemical analyzer in 124 patients with typeⅡ diabetes mellitus and 58 healthy controls.Results The logarithm of urinary Malb/Cr in diabetes group was significantly higher than that of healthy group(P0.001).The logarithm of urinary Malb/Cr was not correlated with blood level of glucose(r=0.001) in diabetic nephropathy,and it was related with amount of 24 hours urinary protein(r=0.403).Conclusion The increase in urinary Malb/Cr indicates the early renal damage in diabetes patients,and it has great significance in diagnosis of early diabetic nephropathy.

Key concepts: Medicine, Urinary system, Diabetic nephropathy, Diabetes mellitus, Internal medicine, Creatinine, Urine, Urology

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