The Cerebral Hemodynamics Study by Using Multislice CT Perfusion Imaging in Normal Adult

Objective To explore the application of multislice CT perfusion imaging in normal adult cerebral hemodynamics.Methods Routine CT was performed in 13 normal adults,then multislice CT perfusion imaging study was made by selecting the basal ganglia slice and its adjacent slice.The contrast material was bolus injected through antecubital vein ,while four layers of dynamic scans were performed for 50 seconds.These slice dynamic images were processed with the CT perfusion software package.Cerebral blood flow (CBF),cerebral blood volume (CBV),and mean transit time (MTT) were measured within the specific regions of interest (ROI) of the brain,and quantitative analysis was performed.Results A gradient of perfusion between gray matter and white matter was showed on multislice CT perfusion imaging in normal adults.CBF,CBV,and MTT were (54.7±11.3)ml/(min·100 g)、(2.9±0.5)ml/100 g、(3.4±0.6)s,respectively in the gray matter and (27.9±6.9)ml/(min·100 g)、(2.4±0.4)ml/100 g、(3.9±0.5)s respectively in the white matter.Conclusion Multislice CT perfusion scanning with deconvolution analysis is a method that has important practical advantages over previously available methods and provided a new imaging method for measuring the cerebral hemodynamics.