The cerebral hemodynamics study by using multislice CT perfusion imaging in normal adult

Objective To explore the application of multislice CT perfusion imaging (MSCTPI) in normal adult cerebral hemodynamics. Methods Routine CT was performed in 30 normal adults,then MSCTPI study was made by selecting the basal ganglia slice and its adjacent slice.The contrast material was bolus injected through antecubital vein,while two layers of dynamic scans were performed for 40 seconds.These 80-slice dynamic images were processed with the CT perfusion software package.Cerebral blood flow (CBF),cerebral blood volume (CBV),and time to peak (TP) were measured within the specific regions of interest (ROI) of the brain,and quantitative analysis was performed. Results A gradient of perfusion between gray matter and white matter was showed on MSCTPI in normal adults.CBF,CBV,and TP were (50.6±9.0) ml·min -1·100 g -1,(57.8±9.1) ml·min -1·100 g -1,and (10.6±1.6) s,respectively in the gray matter,(22.7±8.6) ml·min -1·100 g -1,(30.8±9.8)ml·min -1·100 g -1,and (12.9±2.6) s,respectively in the white matter. Conclusion MSCTPI provided a new imaging method for measuring the cerebral hemodynamics.