Clinical Study on Insulin Pump for Elderly Patients with Type 2 Diabetes

Objective To observe the clinical effect and safety between continuous subcutaneous insulin infusion(CSII) of insulin aspart and Novolin 30R in treating elderly patients with type 2 diabetes mellitus.Methods 50 patients with type 2 DM were randomly divided into A group and B group,Novolin 30R was used in B group and was treated twice daily in morning and evening.CSII of insulin aspart was used in A group(DANA Diabecare).Drug dose was adjusted according to the level of blood glucose.The levels of fasting plasma glucose(FPG),2 hours postprandial glucose(2 h PG),therapeutic time,insulin dose and the incidence of hypoglycemia were compared between the two groups.Results CSII group and Novolin 30R group could decrease blood glucose efficiently(P0.01),the levels of fasting plasma glucose(FPG) was no significant differences in the two groups(P0.05),but 2 hours postprandial glucose(2 h PG) in CSII group was lower than Novolin 30R group(P0.05).The incidence of hypoglycemia in the CSII group was more lower than the Novolin 30R group(P0.05) and especially the incidence of severe hypoglycemia at night.Conclusion Continuous subcutaneous insulin infusion of insulin aspart is an effective and high safety in the treatment of type 2 diabetes mellitus in elderly patients.