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2006•Biaoji mianyi fenxi yu linchuangRequires access

Relationship among NO, ET, hs-CRP, TNF-α and adiponectin levels in coronary heart disease

Tu Zhiming, Di Zhang, Hong Kan, Yifeng Xue, Lingling Gong, LI Jia-ping, Weihong Lu, Fengzeng Jian

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Abstract

To measure NO,ET,hs-CRP,TNF-α and adiponectin levels and to analyse relationships among them in 68 patients with coronary heart disease(CHD) and 20 control subjects(group A),the coronary heart disease subjects according to their blood total cholesterol(TC) level were divided into simple CHD group(B,n=32) and CHD with hypercholesterolemia group(C,n=36).Fasting TC,NO,ET,hs-CRP,TNF-α and adiponectin concentrations were measured in all subjects.The relationships among these factors were analyzed.The serum ET,hs-CRP,TNF-α levels in group B were significantly higher than those in group A,while serum NO and adiponectin levels were significantly lower in group B than those in group A.Adiponectin level was significantly correlated with coronary artery stenosis degree.TC,hs-CRP and adiponectin levels are good indexes in evaluating the CHD.

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What this paper is about

To measure NO,ET,hs-CRP,TNF-α and adiponectin levels and to analyse relationships among them in 68 patients with coronary heart disease(CHD) and 20 control subjects(group A),the coronary heart disease subjects according to their blood total cholesterol(TC) level were divided into simple CHD group(B,n=32) and CHD with hypercholesterolemia group(C,n=36).Fasting TC,NO,ET,hs-CRP,TNF-α and adiponectin concentrations were measured in all subjects.The relationships among these factors were analyzed.The serum ET,hs-CRP,TNF-α levels in group B were significantly higher than those in group A,while serum NO and adiponectin levels were significantly lower in group B than those in group A.Adiponectin level was significantly correlated with coronary artery stenosis degree.TC,hs-CRP and adiponectin levels are good indexes in evaluating the CHD.

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Available abstract

To measure NO,ET,hs-CRP,TNF-α and adiponectin levels and to analyse relationships among them in 68 patients with coronary heart disease(CHD) and 20 control subjects(group A),the coronary heart disease subjects according to their blood total cholesterol(TC) level were divided into simple CHD group(B,n=32) and CHD with hypercholesterolemia group(C,n=36).Fasting TC,NO,ET,hs-CRP,TNF-α and adiponectin concentrations were measured in all subjects.The relationships among these factors were analyzed.The serum ET,hs-CRP,TNF-α levels in group B were significantly higher than those in group A,while serum NO and adiponectin levels were significantly lower in group B than those in group A.Adiponectin level was significantly correlated with coronary artery stenosis degree.TC,hs-CRP and adiponectin levels are good indexes in evaluating the CHD.

Key concepts: Adiponectin, Medicine, Internal medicine, Coronary heart disease, Coronary artery disease, Cardiology, Endocrinology, Obesity

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Relationship among NO, ET, hs-CRP, TNF-α and adiponectin levels in coronary heart disease — Research Paper | ScholarLens