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ANALYSIS OF CLINICAL VALUE OF THE BILEVEL POSITIVE AIRWAY PRESSURE (BIPAP) IN PATIENTS WITH ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (AECOPD) COMBINED WITH TYPE II RESPIRATORY FAILURE

Chen Hao

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Abstract

[Objective] To investigate the clinical application value of the bilevel positive airway pressure (BiPAP) in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) combined with type Ⅱ respiratory fail-ure. [Methods] 42 patients of AECOPD with type Ⅱ respiratory failure were randomly divided into two groups: control group and treatment group. The control group received the routine therapy including anti-infection, eliminating phlegm, wheeze re-mission assistant with low -flow oxygen therapy by endonasal catheter continually; and the treatment group received BiPAP breathing machine assisted ventilation holding on at least 12 hours and the routine therapy. The measures of arterial gas analysis, including pH, PaCO2, PaO2 and SaO2 were observed before and after therapy 72 hours, meanwhile, the hospital days and ex-pense were counted. [ Results] Compared with control group, arterial gas analysis was significantly improved in treatment group. The clinical symptoms relieved rapidly, and the hospital days reduced in treatment group. There was significant difference between the two groups (P﹤0.05). [Conclusion] The organism hypoxia and acidosis are significantly improved in the patients of AECOPD with type Ⅱ respiratory failure who are treated with BiPAP assisted ventilation, the clinical symptoms are alleviat-ed, the hospital days and the financial burden of the patients are alleviated.

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What this paper is about

[Objective] To investigate the clinical application value of the bilevel positive airway pressure (BiPAP) in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) combined with type Ⅱ respiratory fail-ure. [Methods] 42 patients of AECOPD with type Ⅱ respiratory failure were randomly divided into two groups: control group and treatment group. The control group received the routine therapy including anti-infection, eliminating phlegm, wheeze re-mission assistant with low -flow oxygen therapy by endonasal catheter continually; and the treatment group received BiPAP breathing machine assisted ventilation holding on at least 12 hours and the routine therapy. The measures of arterial gas analysis, including pH, PaCO2, PaO2 and SaO2 were observed before and after therapy 72 hours, meanwhile, the hospital days and ex-pense were counted. [ Results] Compared with control group, arterial gas analysis was significantly improved in treatment group. The clinical symptoms relieved rapidly, and the hospital days reduced in treatment group. There was significant difference between the two groups (P﹤0.05). [Conclusion] The organism hypoxia and acidosis are significantly improved in the patients of AECOPD with type Ⅱ respiratory failure who are treated with BiPAP assisted ventilation, the clinical symptoms are alleviat-ed, the hospital days and the financial burden of the patients are alleviated.

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Available abstract

[Objective] To investigate the clinical application value of the bilevel positive airway pressure (BiPAP) in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) combined with type Ⅱ respiratory fail-ure. [Methods] 42 patients of AECOPD with type Ⅱ respiratory failure were randomly divided into two groups: control group and treatment group. The control group received the routine therapy including anti-infection, eliminating phlegm, wheeze re-mission assistant with low -flow oxygen therapy by endonasal catheter continually; and the treatment group received BiPAP breathing machine assisted ventilation holding on at least 12 hours and the routine therapy. The measures of arterial gas analysis, including pH, PaCO2, PaO2 and SaO2 were observed before and after therapy 72 hours, meanwhile, the hospital days and ex-pense were counted. [ Results] Compared with control group, arterial gas analysis was significantly improved in treatment group. The clinical symptoms relieved rapidly, and the hospital days reduced in treatment group. There was significant difference between the two groups (P﹤0.05). [Conclusion] The organism hypoxia and acidosis are significantly improved in the patients of AECOPD with type Ⅱ respiratory failure who are treated with BiPAP assisted ventilation, the clinical symptoms are alleviat-ed, the hospital days and the financial burden of the patients are alleviated.

Key concepts: Medicine, Positive airway pressure, Respiratory failure, Respiratory acidosis, Exacerbation, Anesthesia, Oxygen therapy, Respiratory system

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ANALYSIS OF CLINICAL VALUE OF THE BILEVEL POSITIVE AIRWAY PRESSURE (BIPAP) IN PATIENTS WITH ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (AECOPD) COMBINED WITH TYPE II RESPIRATORY FAILURE — Research Paper | ScholarLens