Observation on therapeutic effect of BiPAP respirator in treatment of cases of acute exacerbation of chronic obstructive pulmonary disease with type II respiratory failure

Objective To explore the clinical efficacy of bilevel positive airway pressure(BIPAP) respirator assisted ventilation in treatment of cases of acute exacerbation of chronic obstructive pulmonary disease(AECOPD) with type Ⅱ respiratory failure.Methods A total of 62 patients of acute exacerbation of chronic obstructive pulmonary disease with type Ⅱ respiratory failure were randomly allocated into two groups: trial group(32 cases) and control group(30 cases).The routine treatment including anti-infectious medication,cleaning airway and continuous inhalation of low concentration oxygen,and pneumatic analeptics was only given to patients of control group,but both BIPAP assisted ventilation and routine treatment were given to patients of trial group.Patients in these two groups were monitored for arterial blood gas parameters and changes of basic vital signs.Results Findings of heart rate,respiration rate,blood pH,PaO2 and PaCO2 in patients of two groups before treatment were compared with those after treatment,these parameters were obviously improved,their difference was significant(P0.05).There was significant difference(P0.05) in these findings between patients in trial group after treatment in comparison with those of patients in control group after treatment.Conclusion BIPAP assisted ventilation is certainly an effective measure for treatment of patients with AECOPD with type Ⅱ respiratory failure.