Investigation of Reference Range of Parameters of Liver and Renal Function of Old People in Beijing

Objective: To observe the reference range of parameters which reflect liver and renal function in different age of old people in Beijing. Methods: A random sample of 600 old people were divided in three groups with different ages. The blood was drawing on empty stomach. The Modular machine and its supported reagent were used to detect the levels of ALT (alanine aminotransferase), AST (aspartate aminotransferase), TP(total protein), ALB(albumin), Bun(blood urea nitrogen), Crea (creatinine) and UA (uric acid). SPSS11.0 was used to analyze results and compare the levels between groups, and the reference range was decided accord to statistical results. A random sample of 371 healthy young people were compared with old people in these parameters. Results: AST, TP, UA had no significant differences in different groups, while ALT, ALB declined with age and Bun, Crea increased with age. Conclusion: Through this experiment, it will conduct the preliminary analysis on the old people' reference range of ALT, AST, TP, ALB, Bun, Crea, UA, and provide suggestion on the current reference range. Each clinical laboratory should establish its own reference range.