2013•Hainan Yixueyuan xuebaoRequires access
Effect of antibiotics and microwave on serum IL-8 and TGF-β_1 in patients with acute pelvic inflammation
WU Neng-li
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Abstract
Objective: To investigate the effect of antibiotic and the microwave treatment on serum IL-8 and TGF-β1 in patients with acute pelvic inflammation.Methods: A total of 168 case with acute pelvic inflammation admitted from April 2010 to April 2011 were selected,and were randomly divided into two groups by half.Patients in control group were given levofloxacin combined with tinidazole treatment,and patients in treatment group were given microwave treatment plus the same treatment and.The course was 14 days.Improvement of clinical symptoms and physical signs was observed,and IL-8 and TGF-β1 were measured by radioimmunoassay.The correlation between them was analyzed.Results: In treatment group after treatment o clinical symptoms and physical signs were significantly improved,serum IL-8 was significantly increased and TGF-β1 was significantly decreased(P0.01).Correlation analysis revealed negative correlation between IL-8 and TGF-β1(P0.05).Conclusion: Antibiotics and microwave treatment is effective in treating acute pelvic inflammatory disease.IL-8 and TGF-β1 can be used as indicators for judging curative effect and prognosis.