Clinical study on the effects of early enteral nutrition in treatment of severe acute pancreatitis

Objective: To evaluate the therapeutic effects of early enteral nutrition in the treatment of severe acute pancreatitis by nasojejunal tube.Methods: Forty-one cases of SAP were retrospectively analyzed and divided into 2 groups.There were 20 cases in conventional therapy group and 21 cases in enteral nutrition group.Major causes,treatments and clinical results were analyzed and APACHEⅡ score,CT score,serum albumin and prealbumin were compared between two groups.Results: Fortyone cases were cured and no one needed surgical intervention except six pateints with pseudocysts.EN cases were fed via a nasojejunal tube placed at the seventh day after admission.EN was well tolerated throughout the course of disease.The improvement of APACHEⅡ score of the EN group was significantly higher than that of conventional therapy group(P0.05).Serum albumin and prealbumin of the EN group were higher than that of conventional therapy group after three weeks treatment and the difference of prealbumin was significant(P0.05).Conclusion: As the major treatment of SAP,EN is feasible,safe and easy to use.Reasonable EN could significantly decrease the APACHEⅡscore and improve the nutrition status of the SAP patients.