Evaluation of cervical conization in diagnosis and management of cervical intraepithelial neoplasia

Aim To explore the value of diagnosis and treatment of cold knife conization to cervical intraepithelial neoplasia(CKC)Ⅲ.Methods Seventy patients with CIN Ⅲ diagnosed and treated were retrospectively analyzed focusing on the comparative study in pathology between colposcopic multiple biopsies and CKC.Results Of the 70 patients,accordance rate of diagnosis was 61.43%,11 cases(15.71%) upgrades,including 9 cases of early invasive carcinoma and 2 cases of invasive carcinoma,16 cases(22.86%) downgrades.28 cases of CIN Ⅲafter hysterectomy cervical pathology showed residual CIN Ⅲ 1 cases,CIN Ⅱ 4 cases,CINI 3 cases,inflammation 20 cases.All cases were closely followed up,no cytology abnormality was detected.Postoperative hemorrhage was the main side effect for CKC.Conclusion CKC can inprove the diagnostic accuracy and prenvent the omission of invasive carcinoma for the patient with CIN Ⅲ.CKC is the first choice of treatment for the patient with CIN Ⅲ.