ScholarLens Back to search
2008•Chinese Journal of Neurosurgical Disease ResearchRequires access

Bcl-2 mRNA expression in hippocampus of mice exposed to infrasound

Xiang Mou

Open publisher page 0 citations

Abstract

Objective To explore the change of bcl-2 mRNA in the hippocampus of mice exposed to infrasound of different sound levels.Methods BALB/C mice were exposed to infrasound of 16 Hz,90/130 dB for 2 h everyday with exposure time of 1,7,14,21 and 28 d respectively.In situ hybridization was used to study the expression of bcl-2 mRNA in hippocampus.Results Reaction of 130 dB group was more intense than that of 90 dB group.While under the same sound pressure level,bcl-2 mRNA in hippocampus increased with the increase of exposure time.Conclusion Hippocampus is sensitive to the infrasound.With the effects on bcl-2 mRNA,infrasound may cause damage to brain,which is one important factor for the brain injury caused by infrasound.The effect is related to the sound pressure level and exposure time.

About this research paper

What this paper is about

Objective To explore the change of bcl-2 mRNA in the hippocampus of mice exposed to infrasound of different sound levels.Methods BALB/C mice were exposed to infrasound of 16 Hz,90/130 dB for 2 h everyday with exposure time of 1,7,14,21 and 28 d respectively.In situ hybridization was used to study the expression of bcl-2 mRNA in hippocampus.Results Reaction of 130 dB group was more intense than that of 90 dB group.While under the same sound pressure level,bcl-2 mRNA in hippocampus increased with the increase of exposure time.Conclusion Hippocampus is sensitive to the infrasound.With the effects on bcl-2 mRNA,infrasound may cause damage to brain,which is one important factor for the brain injury caused by infrasound.The effect is related to the sound pressure level and exposure time.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the change of bcl-2 mRNA in the hippocampus of mice exposed to infrasound of different sound levels.Methods BALB/C mice were exposed to infrasound of 16 Hz,90/130 dB for 2 h everyday with exposure time of 1,7,14,21 and 28 d respectively.In situ hybridization was used to study the expression of bcl-2 mRNA in hippocampus.Results Reaction of 130 dB group was more intense than that of 90 dB group.While under the same sound pressure level,bcl-2 mRNA in hippocampus increased with the increase of exposure time.Conclusion Hippocampus is sensitive to the infrasound.With the effects on bcl-2 mRNA,infrasound may cause damage to brain,which is one important factor for the brain injury caused by infrasound.The effect is related to the sound pressure level and exposure time.

Key concepts: Infrasound, Hippocampus, Messenger RNA, In situ hybridization, Internal medicine, Biology, Endocrinology, Medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Bcl-2 mRNA expression in hippocampus of mice exposed to infrasound — Research Paper | ScholarLens