Effect of Galtnut on Candida albicans biofilm:An in vitro study

Objective:To compare the effects of aqueous extract of Chinese Galtnut,calcium hydroxide and chlorhexidine on candida albicans biofilm.Methods:Biofilms were grown on 96-well polymethylmethacrylate strips,and the quantitative analysis of biofilm formation and the concentrations of three antimicrobials restraining 80% fungal growth was performed by XTT reduction method.Result:The cellular metabolism level at 48h was the highest.The biofilm bioactivity and drug resistance increased with culturing time.Conclusion:Candida albicans were unsensitive to calcium hydroxide but sensitive to chlorhexidine and aqueous extract of Chinese Galtnut can restrain the biofilm formation at the initial stage.