Pathogens causing biliary tract infection and their sensitivity to antibiotics

OBJECTIVE Analyze the distribution of pathogen in biliary tract infection and their sensitivity to antibiotics so as to guide the rational use of antibiotics.METHODS The data of 521 strains of pathogens which were collected from biliary tract infection from Jul 2005 to Jun 2009 were retrospectively analyzed and their sensitivity to antibiotics were also analyzed.RESULTS A total of 521 strains,72.94% of which were Gram negative bacilli and 26.10% of which were Gram positive ones.The most common pathogenic bacteria were Escherichia coli,Klebsiella pneumoniae,Enterococcus faecalis,Pseudomonas aeruginosa and Enterococcus faecium.The results of drug susceptibility showed that Gram-positive bacteria were 100.00% sensitive to vancomycin and teicoplanin.Among the Gram negative bacilli,99.63% of E.coli and 98.75% of K.pneumoniae were sensitive to imipenem.P.aeruginosa was sensitive to amikacin.CONCLUSIONS Gram negative strains are most common in biliary tract infection,but the rate of Gram positive strains is obviously rising.Antibiotic should be selected based on the sensitivity test results in order to reduce bacterial resistance and improve the cure rate.