Pathogens in biliary tract infection and their sensitivity to antibiotics.

OBJECTIVE To investigate the distribution of pathogens in biliary tract bacteria and characteristics of drug resistance and to provide the clinical basis for selection of antibacterial drugs for clinicians. METHODS The data of 253 strains of the pathogens in biliary tract infection and their sensitivity to antibiotics were statistically analyzed by K-B method in accordance with National Clinical Examination Procedures and France's BioMerieax VITEK-32 instrument. RESULTS Among the 253 strains,Gram-negative bacteria accounted for 173( 68.4% ),Gram-positive cocci 74 (29.2%) and fungi for 6 (2.4%). The main Gram-negative bacteria were Escherichia coli,the Gram-positive bacteria were mainly Enterococcus. Thirty-two extended-spectrum β-lactamases (ESBLs) strains were detected,from which E. coli accounted for 24 (75.0%),and Klebsiella for 8(25.2%). CONCLUSIONS The pathogens in biliary tract infection are widely distributed. Some strains have multi-drug resistantce ,so it is important to keep on detecting the culture of biliary bacteria and their drug sensitivity results to reduce the ESBLs producing strains.