2013Chinese and Foreign Medical ResearchRequires access

Clinical Observation of the Ropivacaine and Bupivacaine for Combined Spinal-epidural Anesthesia in Cesarean Sections

XU Ling-zhon

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Abstract

Objective:To evaluate the latency and duration of analgesia and maternal and fetal repercussions with bupivacaine hydrochloride and ropivacaine hydrochloride in combined spinal-epidural anesthesia for cesarean section.Method:120 cases of cesarean section operation singleton term parturients were randomly divided into two groups:Ropivacaine group(group R),patients were given 11 mg ropivacaine;Bupivacaine group(group B),patients received bupivacaine 11 mg.Monitoring the changes of hemodynamics,operation time,compared two groups of sensory block onset time,block level,at the top of the highest time block plane,sensory recovery time,motor block onset time,recovery time,the analgesic effect of movement,the maximum Bromage score,muscle relaxation effect,neonatal Apgar score,assessment of anesthetic effect and tightness in the chest,nausea and vomiting the incidence of adverse reactions.Result:The amount of sensory block onset time,block level reached the highest time in group R were significantly shorter than group B(P0.05),group R of motor block onset time,reaching the highest modified Bromage score was significantly slower than group B(P0.05),and complete recovery time was significantly faster movement than group B(P0.05).The analgesic effect,two groups of muscle relaxation effect,neonatal Apgar score,operation time,recovery time,feeling wrer no significant difference between the two groups in blood pressure and heart rate,compared with group B,a better effect of ropivacaine group,the difference was statistically significant(P0.01),no significant difference in nausea and vomiting,respiratory depression adverse reactions of the two groups after operation.Conclusion:Two kinds of anesthesia methods can meet the clinical needs,but the effect of group R was better than that of group B,and has less adverse reaction.

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Objective:To evaluate the latency and duration of analgesia and maternal and fetal repercussions with bupivacaine hydrochloride and ropivacaine hydrochloride in combined spinal-epidural anesthesia for cesarean section.Method:120 cases of cesarean section operation singleton term parturients were randomly divided into two groups:Ropivacaine group(group R),patients were given 11 mg ropivacaine;Bupivacaine group(group B),patients received bupivacaine 11 mg.Monitoring the changes of hemodynamics,operation time,compared two groups of sensory block onset time,block level,at the top of the highest time block plane,sensory recovery time,motor block onset time,recovery time,the analgesic effect of movement,the maximum Bromage score,muscle relaxation effect,neonatal Apgar score,assessment of anesthetic effect and tightness in the chest,nausea and vomiting the incidence of adverse reactions.Result:The amount of sensory block onset time,block level reached the highest time in group R were significantly shorter than group B(P0.05),group R of motor block onset time,reaching the highest modified Bromage score was significantly slower than group B(P0.05),and complete recovery time was significantly faster movement than group B(P0.05).The analgesic effect,two groups of muscle relaxation effect,neonatal Apgar score,operation time,recovery time,feeling wrer no significant difference between the two groups in blood pressure and heart rate,compared with group B,a better effect of ropivacaine group,the difference was statistically significant(P0.01),no significant difference in nausea and vomiting,respiratory depression adverse reactions of the two groups after operation.Conclusion:Two kinds of anesthesia methods can meet the clinical needs,but the effect of group R was better than that of group B,and has less adverse reaction.

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Available abstract

Objective:To evaluate the latency and duration of analgesia and maternal and fetal repercussions with bupivacaine hydrochloride and ropivacaine hydrochloride in combined spinal-epidural anesthesia for cesarean section.Method:120 cases of cesarean section operation singleton term parturients were randomly divided into two groups:Ropivacaine group(group R),patients were given 11 mg ropivacaine;Bupivacaine group(group B),patients received bupivacaine 11 mg.Monitoring the changes of hemodynamics,operation time,compared two groups of sensory block onset time,block level,at the top of the highest time block plane,sensory recovery time,motor block onset time,recovery time,the analgesic effect of movement,the maximum Bromage score,muscle relaxation effect,neonatal Apgar score,assessment of anesthetic effect and tightness in the chest,nausea and vomiting the incidence of adverse reactions.Result:The amount of sensory block onset time,block level reached the highest time in group R were significantly shorter than group B(P0.05),group R of motor block onset time,reaching the highest modified Bromage score was significantly slower than group B(P0.05),and complete recovery time was significantly faster movement than group B(P0.05).The analgesic effect,two groups of muscle relaxation effect,neonatal Apgar score,operation time,recovery time,feeling wrer no significant difference between the two groups in blood pressure and heart rate,compared with group B,a better effect of ropivacaine group,the difference was statistically significant(P0.01),no significant difference in nausea and vomiting,respiratory depression adverse reactions of the two groups after operation.Conclusion:Two kinds of anesthesia methods can meet the clinical needs,but the effect of group R was better than that of group B,and has less adverse reaction.

Key concepts: Medicine, Ropivacaine, Anesthesia, Bupivacaine, Nausea, Apgar score, Vomiting, Analgesic

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