ScholarLens Back to search
2014•Traditional Chinese MedicineRequires access

Effect of Xiezhuo Jiedu Fang on IL-4 and IL-6 in Serum of Rats With Ulcerative Colitis

Liu Jian-pin

Open publisher page 0 citations

Abstract

Objective:to observe the effect of Xiezhuo Jiedu Fang on IL-4 and IL-6 in serum of rates with UC so as to explore the functional mechanism in treatment of UC with modern medicine.Methods:Rat models with UC induced by combining TNBS and Alcohol were divided into blank group,model group,Sulfasalazine group,low dosage of Xiezhuo Jiedu Fang group and high dosage group.Radio-immunity method was taken to detect IL-4 and IL-6 in serum of rates with UC.Results:Xiezhuo Jiedu Fang could decrease IL-6 content,increase IL-4.Conclusion:Xiezhuo Jiedu Fang is effective in treating UC rats whose mechanism may be related to increasing IL-4,strengthening its action of inhibiting inflammation,decreasing IL-6 and weakening inflammatory reaction.

About this research paper

What this paper is about

Objective:to observe the effect of Xiezhuo Jiedu Fang on IL-4 and IL-6 in serum of rates with UC so as to explore the functional mechanism in treatment of UC with modern medicine.Methods:Rat models with UC induced by combining TNBS and Alcohol were divided into blank group,model group,Sulfasalazine group,low dosage of Xiezhuo Jiedu Fang group and high dosage group.Radio-immunity method was taken to detect IL-4 and IL-6 in serum of rates with UC.Results:Xiezhuo Jiedu Fang could decrease IL-6 content,increase IL-4.Conclusion:Xiezhuo Jiedu Fang is effective in treating UC rats whose mechanism may be related to increasing IL-4,strengthening its action of inhibiting inflammation,decreasing IL-6 and weakening inflammatory reaction.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:to observe the effect of Xiezhuo Jiedu Fang on IL-4 and IL-6 in serum of rates with UC so as to explore the functional mechanism in treatment of UC with modern medicine.Methods:Rat models with UC induced by combining TNBS and Alcohol were divided into blank group,model group,Sulfasalazine group,low dosage of Xiezhuo Jiedu Fang group and high dosage group.Radio-immunity method was taken to detect IL-4 and IL-6 in serum of rates with UC.Results:Xiezhuo Jiedu Fang could decrease IL-6 content,increase IL-4.Conclusion:Xiezhuo Jiedu Fang is effective in treating UC rats whose mechanism may be related to increasing IL-4,strengthening its action of inhibiting inflammation,decreasing IL-6 and weakening inflammatory reaction.

Key concepts: Sulfasalazine, Ulcerative colitis, Medicine, Pharmacology, Gastroenterology, Internal medicine, Disease

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effect of Xiezhuo Jiedu Fang on IL-4 and IL-6 in Serum of Rats With Ulcerative Colitis — Research Paper | ScholarLens