Gender Difference of the Relationship between Serum Uric Acid and Metabolic Syndrome

Objective To study the relationship between serum uric acid(SUA) and metabolic syndrome(MS) and its components in middle-aged and elderly Chinese.Methods A cross-sectional study was used to investigate 711 subjects between the ages of 49 to 80 in the year of 2007 in Chenghua District of Chengdu City.Body height,weight,blood pressure,fasting blood glucose,triglyceride,high-density and low-density lipoprotein,and serum uric acid level were detected,and the relationships between SUA and MS,SUA and each component of MS were analyzed using SPSS 16.0.Results MS rate was 25.60% in the middle-aged and elderly subjects.Hyperuricemia rate was 21.24%.The prevalence of MS,abdominal obesity,hypertriglyceridemia and low high-density lipoprotein acidosis was significantly higher in women than in men.The correlation coefficients between SUA and waistline,systolic blood pressure,triglycerides,diastolic blood pressure,and high-density lipoprotein cholesterol were respectively 0.311,0.140,0.118,0.106 and-0.147.The correlation coefficient between uric acid and waistline in male and female was respectively 0.173 and-0.321.The correlation coefficient between uric acid and fasting blood glucose in male and female was respectively-0.049 and 0.183.All the differences had statistical significances.Conclusions SUA is closely related to MS and MS components.The relationship between them has gender difference.