Treatment of impaired glucose tolerance of type of qi stagnation and phlegm retention with modified Yueju Decoction

Objective To observe the curative effect of modified Yueju Decoction on impaired glucose tolerance(IGT) of type of qi stagnation and phlegm retention.MethodsThe patients of IGT of qi stagnation and phlegm retention(n=90) were randomly divided into the blank group(n=30),Chinese medicinal group(n=30) and Western medicinal group(n=30),and was,respectively,given the basic treatment,basic treatment and Yueju Decoction and basic treatment and acarbose.The changes of plasma glucose,glycated hemoglobin(HbA1c),insulin function,lipid metabolism and body mass index(BMI) were observed,and the outcomes of three groups were reviewed after the treatment.ResultsCompared with the blank group,the levels of 2-hour postprandial blood glucose(PBG) and HbA1c decreased significantly and insulin(INS) increased(P0.01),and the indexes of triglyceride(TG),total cholesterol(TC),low-density lipoprotein(LDL) and BMI were improved significantly(P0.05) in the Chinese medicinal group and Western medicinal group.The transformation rate of normal glucose tolerance(NGT) was higher in the Chinese medicinal group and Western medicinal group than that in the blank group(P0.05).ConclusionModified Yueju Decoction can relieve IGT,improve insulin function and correct the disorder of lipid metabolism.It can reverse IGT to normal glucose tolerance to a certain degree and the curative effect is as same as acarbose.