Clinical Distribution and drug-resistance of Pseudomonas aeruginosa infection in intensive care unit

Objective To investigate clinical distribution and drug-resistance of Pseudomonas aeruginosa infection in intensive care unit(ICU),and to guide clinical use of antibiotics.Methods The clinical datum of 205 cases of infection in ICU caused by Pseudomonas were retrospectively analyzed.Results Pseudomonas aeruginosa were mainly isolated from sputum(70.7%),secretions and blood,drug-resistance status of Pseudomonas aeruginosa were very serious in local hospital,Pseudomonas kept highly susceptibility to polymyxin B and cefoperazone / Shubatan,Amikacin,imipenem and piperacillin / tazobactam,resistance rates were 17.6%,22.7% and 28.1%.Other antibiotic resistance rates were higher than 55%.Conclusion Clinical isolates of Pseudomonas aeruginosa are from the respiratory tract,drug resistance rates are high,multiple resistance and resistant strains emerged,it should strengthen the ICU monitoring of drug resistance of Pseudomonas aeruginosa,prevent drug-resistant strains in nosocomial transmission of epidemic.