The Effect on Immunological Function Induced by Jianli Capsule in Mice
Run Chen
Abstract
Run Chen
Abstract
[Objective]To observe the effect on Immunological functions induced by Jianli capsule in mice.[Methods]Jianli capsule were given orally to BALB/c mice for 30 days with three dosage groups of 250 mg/kg·bw,500 mg/kg·bw and 1 500 mg/kg·bw.The ratio of organ weight to body weight,the functions of cell immunity,humoral immunity,the function of mononuclearmacrophage and the activity of NK were tested.[Results]The ratio of spleen to body weight,the ability for clearance of carbon,the phagocytic power of celiac macrophage to chicken erythrocyte in all dosage group were not changed.In 1 500 mg/kg·bw dosage group,indexes including the ratio of thymus to body weight,the amount of serum hemolytic antibody,the production of antibody-producing cells,the appreciation ability of spleen lymph-cell under the derivation of ConA,and the activity of NK were significantly increased.The response of delayed hypersensitivity in both 500 mg/kg·bw group and 1 500 mg/kg·bw group had been improved.[Conclusion]Jianli capsule may improve the immunologic function in mice.
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[Objective]To observe the effect on Immunological functions induced by Jianli capsule in mice.[Methods]Jianli capsule were given orally to BALB/c mice for 30 days with three dosage groups of 250 mg/kg·bw,500 mg/kg·bw and 1 500 mg/kg·bw.The ratio of organ weight to body weight,the functions of cell immunity,humoral immunity,the function of mononuclearmacrophage and the activity of NK were tested.[Results]The ratio of spleen to body weight,the ability for clearance of carbon,the phagocytic power of celiac macrophage to chicken erythrocyte in all dosage group were not changed.In 1 500 mg/kg·bw dosage group,indexes including the ratio of thymus to body weight,the amount of serum hemolytic antibody,the production of antibody-producing cells,the appreciation ability of spleen lymph-cell under the derivation of ConA,and the activity of NK were significantly increased.The response of delayed hypersensitivity in both 500 mg/kg·bw group and 1 500 mg/kg·bw group had been improved.[Conclusion]Jianli capsule may improve the immunologic function in mice.
Key concepts: Spleen, Capsule, Immunity, Antibody, Humoral immunity, Immunology, Body weight, Immune system