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Diagnostic value of cystatin C detection for the early renal injury in children with Henoch-Schonlein purpura

Huang Yu-g

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Abstract

Objective To study the clinical value of serum Cys C levels in the patients with nonage renal function injury caused by Henoch-Schonlein purpura.Methods Using radioimmouology analytic technique to measure the blood levels of cystatin C and urine albumin excretion rate(UAER),and using enzymic method to detect Scr levels in serum in 48 children with Henoch-Schonlein purpura.Results The levels of serum Cys C in the HSP groups were siganificantly higher than those in control group(P0.05,P0.01),and the serum Cys C levels increased when the urine albumin excretion rate (UAER) increased. The levels of Cys C was positively correlated with UAER and Scr (P0.01,P0.05). Abnormal rate of Cys C was higer than that of Scr in children with Henoch-Schonlein purpura (P0.01,P0.05).Conclusion Serum Cys C has important clinical value in the early diagnosis of renal injury in children with Henoch-Schonlein purpura.

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Objective To study the clinical value of serum Cys C levels in the patients with nonage renal function injury caused by Henoch-Schonlein purpura.Methods Using radioimmouology analytic technique to measure the blood levels of cystatin C and urine albumin excretion rate(UAER),and using enzymic method to detect Scr levels in serum in 48 children with Henoch-Schonlein purpura.Results The levels of serum Cys C in the HSP groups were siganificantly higher than those in control group(P0.05,P0.01),and the serum Cys C levels increased when the urine albumin excretion rate (UAER) increased. The levels of Cys C was positively correlated with UAER and Scr (P0.01,P0.05). Abnormal rate of Cys C was higer than that of Scr in children with Henoch-Schonlein purpura (P0.01,P0.05).Conclusion Serum Cys C has important clinical value in the early diagnosis of renal injury in children with Henoch-Schonlein purpura.

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Available abstract

Objective To study the clinical value of serum Cys C levels in the patients with nonage renal function injury caused by Henoch-Schonlein purpura.Methods Using radioimmouology analytic technique to measure the blood levels of cystatin C and urine albumin excretion rate(UAER),and using enzymic method to detect Scr levels in serum in 48 children with Henoch-Schonlein purpura.Results The levels of serum Cys C in the HSP groups were siganificantly higher than those in control group(P0.05,P0.01),and the serum Cys C levels increased when the urine albumin excretion rate (UAER) increased. The levels of Cys C was positively correlated with UAER and Scr (P0.01,P0.05). Abnormal rate of Cys C was higer than that of Scr in children with Henoch-Schonlein purpura (P0.01,P0.05).Conclusion Serum Cys C has important clinical value in the early diagnosis of renal injury in children with Henoch-Schonlein purpura.

Key concepts: Medicine, Henoch-Schonlein purpura, Purpura (gastropod), Cystatin C, Urine, Internal medicine, Excretion, Gastroenterology

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Diagnostic value of cystatin C detection for the early renal injury in children with Henoch-Schonlein purpura — Research Paper | ScholarLens