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2006•Chinese Journal of Laboratory DiagnosisRequires access

Gastrointestinal stromal tumors:A pathomorphologic and immunohistochemical study of 67 cases

Song Din

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Abstract

Objective To investigate the pathological and immunohistochemical features of gastrointestinal stromal tumors(GIST).Methods 67 cases of GIST were studied by routine stain and immunohistochemistry.Results 61.2% of the tumors originated in the small intestine.The neoplastic cells of GIST were spindle,epithelioid or both in different proportion,have a lesser degree of cytoplasmic eosinophilia.The immunophenotype of GIST was CD34+,CD117+.Conclusion GIST is with special immunophentype.The immunnohistochemistry is useful for differential diagnosis.

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What this paper is about

Objective To investigate the pathological and immunohistochemical features of gastrointestinal stromal tumors(GIST).Methods 67 cases of GIST were studied by routine stain and immunohistochemistry.Results 61.2% of the tumors originated in the small intestine.The neoplastic cells of GIST were spindle,epithelioid or both in different proportion,have a lesser degree of cytoplasmic eosinophilia.The immunophenotype of GIST was CD34+,CD117+.Conclusion GIST is with special immunophentype.The immunnohistochemistry is useful for differential diagnosis.

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Available abstract

Objective To investigate the pathological and immunohistochemical features of gastrointestinal stromal tumors(GIST).Methods 67 cases of GIST were studied by routine stain and immunohistochemistry.Results 61.2% of the tumors originated in the small intestine.The neoplastic cells of GIST were spindle,epithelioid or both in different proportion,have a lesser degree of cytoplasmic eosinophilia.The immunophenotype of GIST was CD34+,CD117+.Conclusion GIST is with special immunophentype.The immunnohistochemistry is useful for differential diagnosis.

Key concepts: GiST, CD117, Immunohistochemistry, CD34, Immunophenotyping, Pathology, Stromal cell, Pathological

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