Analysis on the antibiotic resistance of 377 strains of Escherichia coli

Objective To investigate the antibiotic resistance of Escherichia coli(E.coli) in Xinqiao Hospital and provide the credible antimicrobial susceptibility test(ATB) results for clinical antibiotic use.Methods A total of 377 clinical isolates of E.coli were collected from different districts of Xinqiao Hospital from January 1999 to December 2002.Bacteria were identified with API system.K B methods were performed to detect the drug resistances of these strains.Results E.coli was sensitive to imipenem,piperacillin tazobactam,nitrofurantoin,ceftazidime,amikacin and the antibiotic resistance was 7.20%,10.83%,14.70%,16.62%,18.65%,respectively.E.coli was resistant to amoxicillin,piperacillin,trimethoprim/sulfa,ampicillin and the antibiotic resistances were all above 70%.Conclusion E.coli is one of the important pathogens that cause extensive clinical infections.Clinical antibiotic use should accord to the AST results.