The diagnostic and efficacy monitoring values of the joint measurements of serum CA125,CEA,AFP and CA724 in patients with ovarian cancer

Objective To explore the diagnostic and efficacy monitoring value of the joint measurements of serum CA125,CEA,AFP and CA724 in patients with ovarian cancer.Methods The levers of CA125,CEA,AFP and CA724 in 30 patients with ovarian cancer,40 patients with benign ovarian tumor and 50 healthy controls were measured by chemistry luminescence immunoassay method.Results Serum CA125,CEA,AFP and CA724 levels on admission in the ovarian cancer patients were significantly higher than those in the benign ovarian tumor patients and healthy controls(P0.01).The sensitivity and diagnosis of the joint measurement of serum CA125,CEA,AFP and CA724 levels were obviously better than those of a single measurement(P0.01).They were compared in the three different periods of treatment in ovarian cancer patients,and there was a substantial difference(P0.01).The better the efficacy was,the lower the concentration was(P0.01).Conclusion Serum CA125,CEA,AFP and CA724 concentrations in patients with ovarian cancer significantly increase,and the clinical diagnosis and efficacymonitoring of the four combined measurements in patients with ovarian cancer have important significance.