2010•Chinese Journal of Clinical Rational Drug UseRequires access
The effect of using victoria A acid,arsenic trioxide,daunorubicin to cure of acute promyelocytic leukemia
Song Guang-ca
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Abstract
Objective To study effect of using victoria A acid,arsenic trioxide,daunorubicin to cure of acute promyelocytic leukemia.Methods 30 cases petients with acute promyelocytic leukemia were randomly divided into control group and observation group,all 15 patients.Control group were gave asingle-agent induction chemotherapy with victoria A acid,while observation group with victoria A acid,arsenic trioxide,daunorubicin induction chemotherapy.Compared clinical effect between two groups.Results Time of complete remission and the percentage of promyelocyte in peripheral blood were significantly improvement in observation group,no-victoria A acid syndrome happened,and tolerance of patients was good.Conclusion Induction chemotherapy of using victoria A acid,arsenic trioxide,daunorubicin for acute promyelocytic leukemia patients should be the first choice management modality.