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The clinical observation of arsenic trioxide in previously untreated patients of acute promyelocytic leukemia

Huang Ren-wei

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Abstract

Objective the clinical effects of arsenic trioxide in previously untreated patients of acute promyelocytic leukemia. Methods As2O3 was given to twenty-two previously untreated patients, and DA regimens were used as maintenance treatment. Continual complete remission and adverse effects were followed. Results complete remission rate was 81.8%. The longest survival time was five years. Conclusions arsenic trioxide is effective in the treatment of APL.

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What this paper is about

Objective the clinical effects of arsenic trioxide in previously untreated patients of acute promyelocytic leukemia. Methods As2O3 was given to twenty-two previously untreated patients, and DA regimens were used as maintenance treatment. Continual complete remission and adverse effects were followed. Results complete remission rate was 81.8%. The longest survival time was five years. Conclusions arsenic trioxide is effective in the treatment of APL.

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Available abstract

Objective the clinical effects of arsenic trioxide in previously untreated patients of acute promyelocytic leukemia. Methods As2O3 was given to twenty-two previously untreated patients, and DA regimens were used as maintenance treatment. Continual complete remission and adverse effects were followed. Results complete remission rate was 81.8%. The longest survival time was five years. Conclusions arsenic trioxide is effective in the treatment of APL.

Key concepts: Arsenic trioxide, Acute promyelocytic leukemia, Medicine, Complete remission, Arsenic, Adverse effect, Internal medicine, Leukemia

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