Comparison on the impairments of different kinds of Luzhou-flavor liquor on rats' liver

Objective The aim of this research was to evaluate the different damages to liver caused by different quality of Luzhou-flavor liquor. Methods 55 healthy male SD rats were randomly divided into: wine sample group ①, wine sample group ②,alcohol control group(48% ethanol solution) and blank control group, lavaged these rats with chronic alcoholism for 30 days. Impairments of liver were observed after the rats were sacrificed and detected serum oxidative damage index included T- SOD, MDA;liver function indexes included ALT, AST, GGT; blood fat indexed included TG, HDL- C, CHOL; serum, made pathology section;used SPSS16.0 to do the statistical analysis. Results There was a statistical difference(P0.05) between two Luzhou-flavor liquor groups which were administered intragastrically for 30 days. Compared with the group ①, the content of SOD was lower(P0.05),MDA was higher(P0.05); ALT, AST, GGT, HDL-C, CHOL were higher(P0.05) in group ②; compared to the blank group, the liver coefficient, TG were higher(P0.05), and compared to the group ①, group ② had serious damage in pathology. Conclusion After lavaging rats for 30 days, compared to the group ①, the extent of damage in liver is serious in the group ②, which demonstrates that different kinds of liquor will do harm to the liver at different levels.