The effects of labor analgesia for subarachnoid-epidural analgesia with different doses of ropivacaine combined with sufentanil

Objective To compare the effects of subarachnoid-epidural analgesia with different doses of ropivacaine com bined with sufentanil during labor analgesia.Methods 27 primipara withrequisition for labor analgesia were randomly divided into 9 groups(3 cases/group),and there were 9 doses combined with different doses of ropivacaine(2.0 mg,2.5 mg,3.0 mg) and sufentanil(1.5 μg,2.0 μg,2.5 μg).All patients were injected intrathecally corresponding doses of ropiva caine combined with sufentanil after combined spinal-epidural anesthesia,then an epiduralcatheter placed for patient-controlled epidural analgesis.The difference of analgesia effects between the groups were evaluated with the onset and dura tion of subarachnoid analgesia by?analysis of variance of factorial design.Results There was no significant difference for the onset in the 9 doses of ropivacaine combined with sufentanil(F = 0.462,P = 0.762),but significantly difference for duration,especially the longest duration came from theropivacaine(2.5 mg) combined with sufentanil(2.5 μg)(F = 3.297,P = 0.034).Conclusion The best effects of labor analgesia was ropivacaine(2.5 mg) combined with sufentanil(2.5 μg) combined spinal-epidural anesthesia.