ScholarLens Back to search
2012•Chinese Journal of Health Laboratory TechnologyRequires access

Analysis of combined dectection of ANA,ENA and dsDNA in 173 Systemic Lupus Erythematosus patients

Yue Ma

Open publisher page 0 citations

Abstract

Objective:To evaluate the diagnostic valve of combined detection of ANA,ENA and dsDNA in systemic lupus enythmatosus.Methods:Serum was collected from 173 patients.ANA as well as dsDNA was tested by indirect immunofluorescent method,and ENA was tested by western blot.Results:The detection rates of the three antibodies in female SLE patients were higher than those of male patients.In the serum of patients,the detection rates of ANA,ASA(anti-sm antibodies) and dsDNA were 94.8%,32.2% and 45.1% respectively.Conclusion:There were significant differences in the sensitivity of ANA,ENA and dsDNA in systemic lupus erythematosus.Combined detection of ANA,ENA and dsDNA autoantibody had the diagnostic value to SLE.

About this research paper

What this paper is about

Objective:To evaluate the diagnostic valve of combined detection of ANA,ENA and dsDNA in systemic lupus enythmatosus.Methods:Serum was collected from 173 patients.ANA as well as dsDNA was tested by indirect immunofluorescent method,and ENA was tested by western blot.Results:The detection rates of the three antibodies in female SLE patients were higher than those of male patients.In the serum of patients,the detection rates of ANA,ASA(anti-sm antibodies) and dsDNA were 94.8%,32.2% and 45.1% respectively.Conclusion:There were significant differences in the sensitivity of ANA,ENA and dsDNA in systemic lupus erythematosus.Combined detection of ANA,ENA and dsDNA autoantibody had the diagnostic value to SLE.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To evaluate the diagnostic valve of combined detection of ANA,ENA and dsDNA in systemic lupus enythmatosus.Methods:Serum was collected from 173 patients.ANA as well as dsDNA was tested by indirect immunofluorescent method,and ENA was tested by western blot.Results:The detection rates of the three antibodies in female SLE patients were higher than those of male patients.In the serum of patients,the detection rates of ANA,ASA(anti-sm antibodies) and dsDNA were 94.8%,32.2% and 45.1% respectively.Conclusion:There were significant differences in the sensitivity of ANA,ENA and dsDNA in systemic lupus erythematosus.Combined detection of ANA,ENA and dsDNA autoantibody had the diagnostic value to SLE.

Key concepts: Autoantibody, Medicine, Anti-dsDNA antibodies, Antibody, Immunology, Lupus erythematosus, Internal medicine, Significant difference

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Analysis of combined dectection of ANA,ENA and dsDNA in 173 Systemic Lupus Erythematosus patients — Research Paper | ScholarLens