Analysis of deproteinized extract of calf blood(DECB) in treatment of ischemic cerebral infarction

AIM:To explore the application value of deproteinized extract of calf blood (DECB) in patients with ischemic cerebral infarction. METHODS:66 cases of patients with ischemic cerebral infarction were randomly divided into control group and DECB treatment group. DECB treatment group was given 30 mL DECB intravenous drip,once a day,for three weeks. Control group was not given DECB treatment in addtion with other treatment. The hemorheology and neurological deficits and changes in the two groups of patients were analyzed before and after treatment. RESULTS:The obvious effective rate of DECB treatment group was 72.7%,which was significantly higher than that in control group (45.5%,P0.05). After treatment,the whole blood viscosity (low shear),hematocrit and platelet aggregation in DECB treatment group were significantly lower than those in control group (P0.05). which were also significantly lower than pre-treatment (P0.05). The plasma viscosity had no statistical difference between the groups. The score of neurological deficit of DECB treatment group was significantly lower than that in control group (P0.05). CONCLUSION:The DECB has the exact efficacy on patients of ischemic cerebral infarction. No adverse reactions were found in clinic. It can be used in clinical practice.