Analysis of yeast-like fungi from hospital samples during three years

Objective To investigate the characteristics of the distribution and the drug resistance of yeast-like fungi isolated from patients in our hospital from 2004 to 2007.Methods The fungi were cultrured by SAD and identified by API identifiaction system.The antifungal susceptibility was detected by Bact-IST analysis system.Results 238 stains of yeast-like fungi which belonged to 8 species were isolated from 338 samples.Candida albicans was predominant,accounted for 68.69 %,followed by C.tropicalis,C.glabrata,C.parapsiosis.70 stains of Candida were resistant to antifungal drugs in variable degrees.The resistant rate of C.albicans To Amphotericin B and Nystatin were 11.43% and 10%,respectively.The resistant rate of C.albicans to Fluconazole and Itraconazole were 18.25% and 25.92%,respectively.Conclusions Candida albicans was the predominant opportunity pathogenic Candida in our hospital during the last 3 years.The Fluconazole and the Itraconazole were detected with the highest rate of resistamce of C.albicans