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Study on the Extraction Technology of Ergejiejiu Granule with Orthogonal Test

Li Li

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Abstract

Objective To optimize the extraction technology of Ergejiejiu Granule.Methods Orthogonal test was carried out.The influence of solvent concentration,the dosage of solvent,and time of extraction on extraction results were investigated with the content of puerarin as index.Results The optimum extraction was described as follows:the concentration of alcohol was 50%,volume of alcohol was 10 times amount of raw herb,and the herb was extracted 3 times with 1.5 h and 80℃ for each time.Conclusion High content of puerarin is obtained with the present technology.The method is stable and replicable and it can provide reference for preparation of Ergejiejiu Granule.

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What this paper is about

Objective To optimize the extraction technology of Ergejiejiu Granule.Methods Orthogonal test was carried out.The influence of solvent concentration,the dosage of solvent,and time of extraction on extraction results were investigated with the content of puerarin as index.Results The optimum extraction was described as follows:the concentration of alcohol was 50%,volume of alcohol was 10 times amount of raw herb,and the herb was extracted 3 times with 1.5 h and 80℃ for each time.Conclusion High content of puerarin is obtained with the present technology.The method is stable and replicable and it can provide reference for preparation of Ergejiejiu Granule.

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Available abstract

Objective To optimize the extraction technology of Ergejiejiu Granule.Methods Orthogonal test was carried out.The influence of solvent concentration,the dosage of solvent,and time of extraction on extraction results were investigated with the content of puerarin as index.Results The optimum extraction was described as follows:the concentration of alcohol was 50%,volume of alcohol was 10 times amount of raw herb,and the herb was extracted 3 times with 1.5 h and 80℃ for each time.Conclusion High content of puerarin is obtained with the present technology.The method is stable and replicable and it can provide reference for preparation of Ergejiejiu Granule.

Key concepts: Granule (geology), Chromatography, Puerarin, Solvent, Raw material, Solvent extraction, Alcohol, Chemistry

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