The serum level of Insulin, IL-6 and CRP in Unstable Angina Patients

Objective The present study aimed to evaluate the serum levels of pro-inflammatory cytokines(IL-6、CRP)and insulin in unstable angina patients. Methods The study included 50 patients with unstable angina divided into a male group which contained 26 male patients, and a female group which contained 24 female patients, all of which with an age range of 35 – 73 years. Control groups contained forty healthy individuals divided into a male group which contained 26 healthy males s, and a female group which contained 24 females, all of which with an age range of 33~70years.Then collect a surum of all the participants to detect the level of Insulin, IL-6 and CRP. Results The levels of insulin,IL-6 and CRP were considerably elevated throughout(P0.01), an optimistic relationship concerning insulin with CRP(r=0.442)and IL-6(r=0.481)in unstable angina patients. Conclusion There was increase in the level of insulin regarding patients with unsteady angina as a result of insulin resistance that was caused by the elevated level of proinflammatory cytokine(CRP,IL-6).