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2010•Practical Journal of Cardiac Cerebral Pneumal and Vascular DiseaseRequires access

Significance of the Alterations of Level of Serum Th17 Type Cytokines in Patients with Unstable Angina

XU Zi-xin

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Abstract

Objective To find out the significance of the the Th17 type cytokines in unstable angina.Methods Peripheral blood were collected from 30 patients with unstable angina(UA group),16 patients with stable angina(SA group ) and 20 patients with the chest pain syndrome(CPS group ).Plasma levels of interleukin-17(IL-17 ),IL-6 and tumor necrosis factor alpha ( TNF-α) were measured by ELISA.Results Plasma levels of IL-17,IL-6 and TNF-α were significantly increased in UA group compared with SA group and CPS group(P 0.05)and there were no difference between in SA group and in CPS group(P0.05).Conclusion The levels of Th17 type cytokines increase in unstable angina.Th17 may take part in the progression of atherosclerosis and lead to unstable angina.

About this research paper

What this paper is about

Objective To find out the significance of the the Th17 type cytokines in unstable angina.Methods Peripheral blood were collected from 30 patients with unstable angina(UA group),16 patients with stable angina(SA group ) and 20 patients with the chest pain syndrome(CPS group ).Plasma levels of interleukin-17(IL-17 ),IL-6 and tumor necrosis factor alpha ( TNF-α) were measured by ELISA.Results Plasma levels of IL-17,IL-6 and TNF-α were significantly increased in UA group compared with SA group and CPS group(P 0.05)and there were no difference between in SA group and in CPS group(P0.05).Conclusion The levels of Th17 type cytokines increase in unstable angina.Th17 may take part in the progression of atherosclerosis and lead to unstable angina.

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Available abstract

Objective To find out the significance of the the Th17 type cytokines in unstable angina.Methods Peripheral blood were collected from 30 patients with unstable angina(UA group),16 patients with stable angina(SA group ) and 20 patients with the chest pain syndrome(CPS group ).Plasma levels of interleukin-17(IL-17 ),IL-6 and tumor necrosis factor alpha ( TNF-α) were measured by ELISA.Results Plasma levels of IL-17,IL-6 and TNF-α were significantly increased in UA group compared with SA group and CPS group(P 0.05)and there were no difference between in SA group and in CPS group(P0.05).Conclusion The levels of Th17 type cytokines increase in unstable angina.Th17 may take part in the progression of atherosclerosis and lead to unstable angina.

Key concepts: Medicine, Unstable angina, Stable angina, Proinflammatory cytokine, Tumor necrosis factor alpha, Internal medicine, Gastroenterology, Angina

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Significance of the Alterations of Level of Serum Th17 Type Cytokines in Patients with Unstable Angina — Research Paper | ScholarLens