ScholarLens Back to search
2007•Zhongguo redai yixueRequires access

Effect of the grape seed procyanidins extract on MDA、SOD and GSH-Px in senile mice

HU Yu-ming

Open publisher page 0 citations

Abstract

Objective To observae the effect of grape seed procyanidins extract (GSPE) on the content of MDA, the activityh of SOD and GSH-Px in senile mice. Methods According to the levles of blood MDA, 40 Kunming senile mice were divided into control group, the groups of low, middle and high dose of GSPE. The content of blood MDA, activity of serum SOD and GSH-PX were determined 30 days after the mice were orally given GSPE. Results Compared with the senile control group, the content of MDA in the blood of high dosage group could obviously be reduced and the activity of serum SOD could be markedly enhanced (P0.05). The effect of GSPE on the serum GSH-Px activity (P0.05). Conclusion GSPE can reduce the content of MDA and enhance the activity of serum SOD in mice.

About this research paper

What this paper is about

Objective To observae the effect of grape seed procyanidins extract (GSPE) on the content of MDA, the activityh of SOD and GSH-Px in senile mice. Methods According to the levles of blood MDA, 40 Kunming senile mice were divided into control group, the groups of low, middle and high dose of GSPE. The content of blood MDA, activity of serum SOD and GSH-PX were determined 30 days after the mice were orally given GSPE. Results Compared with the senile control group, the content of MDA in the blood of high dosage group could obviously be reduced and the activity of serum SOD could be markedly enhanced (P0.05). The effect of GSPE on the serum GSH-Px activity (P0.05). Conclusion GSPE can reduce the content of MDA and enhance the activity of serum SOD in mice.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To observae the effect of grape seed procyanidins extract (GSPE) on the content of MDA, the activityh of SOD and GSH-Px in senile mice. Methods According to the levles of blood MDA, 40 Kunming senile mice were divided into control group, the groups of low, middle and high dose of GSPE. The content of blood MDA, activity of serum SOD and GSH-PX were determined 30 days after the mice were orally given GSPE. Results Compared with the senile control group, the content of MDA in the blood of high dosage group could obviously be reduced and the activity of serum SOD could be markedly enhanced (P0.05). The effect of GSPE on the serum GSH-Px activity (P0.05). Conclusion GSPE can reduce the content of MDA and enhance the activity of serum SOD in mice.

Key concepts: Grape seed, Chemistry, Glutathione, Food science, Superoxide dismutase, Pharmacology, Positive control, Traditional medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effect of the grape seed procyanidins extract on MDA、SOD and GSH-Px in senile mice — Research Paper | ScholarLens