1,6 two phosphate fructose treatment viral myocarditis clinical observation

Objective To explore 1,6 fructose diphosphate intravenous dripping of the treatment for viral myocarditis the clinical effect.Methods To select 60 fire viral myocarditis cases which accept the treatment in our hospital from 2006 January to 2009 July.Then randomly divide them into tow groups: one is for treatment and the other one is for comparison.The two groups have the same foundation treatment.And the 35 examples in the treatment group use 1,6 phosphoric acid fructose 100 ～250mg(kg·d) intravenous dripping note.25 patients in compared group was added Vitc100～200mg/(kg·d) intravenous infusion,for 14 days treatment.Results For two weeks later,94% of the patients' symptoms completely disappeared(33/35),and in the compared group is 84%(21/25)(P 0.01).After the treatment,the ECG of the patients changed.In all the the patients,the proportion of whose symptoms had resume in the treatment group is 91%(32/35).While in the compared group is 56%(14/25)(P0.05).Two weeks later both of the two groups came back to nomal.56%(9/16)(P0.05) of the ventricular premature pulse group come back to normal in two weeks.myocardium enzyme test:in the 2nd week,CK-MB,cTnT,the recoverd is 83%.77% in all,and 50%,52% come back to normal(P10.05,P20.01),in 2～3 months,there is few differences between the normal myocardium enzyme and abnormal myocardium enzyme(P0.05).Conclusion About the viral myocarditis,using 1,6 fructose diphosphate can short the course of disease than using large dose Vitc,from the situation of the clinlcal symptom,physical sign.electrocardiogram,myocardium enzyme,1,6 fructose diphosphate is the effective way to cure myocarditis