Clinical effect of SulfontanshinoneIIA Sodium Injection plus prednisone in primary nephrotic syndrome

Objective To discuss the efficacy of Sulfontanshinone ⅡA Sodium Injection combined with prednisone for primary nephrotic syndrome. Methods 48 patients with PNS were randomized into two groups.24 patients in control group were treated with full dosage of prednisone and conventional therapy,24 patients in treatment group received full dosage of prednisone,conventional therapy and intravenous Sulfontanshinone ⅡA Sodium . Rennal function,blood fat and 24-hour urine protein were detected. Results 24-hour urine protein in patients of both groups were all decreased;total effective rate was 90.7%in treatment group and 78% in control group. As compared with control group,blood fat and renal function in treatment group were improved significantly(P 0.05).Conclusion Sulfontanshinone ⅡA Sodium Injection combined with prednisone may improve PNS.