Fentanyl-propofol compound analgesic effect in the operation of induced abortion and nursing

Objective To discuss the analgesic effect and nursing of fentanyl and propofol on induced abortion. Methods Divided 1650 early pregnant women into two groups at random. In the experimental group, the pregnant women to receive induced abortion operation were performed slowly intravenous injection of 0.05mg fentanyl and 2mg/kg propofol. If necessary, larger dosage of propofol (maximum 0.5mg/kg) was supplemented. In the control group, the traditional induced abortion operation was performed free of analgesic. Observed and compared the analgesic effect, relaxation effect of uterus malformation, satisfaction, pain-oblivion degree, on-operation information, and changes of MAP, HR, and SpO2. Results 100% analgesic effect was achieved in the experimental group abortion syndrome occurrence rate, relaxation effect of uterus malformation, satisfaction, and pain-oblivion degree were obviously better than the control group (P0.01). During and after the operation, MAP, SpO2 of the experimental group was remarkably lowered (P0.01). The occurrence rate of respiratory depression (SpO290%) counted only for 1.05%. MAP, HR of the control group were remarkably increased (P0.01) during and after the operation. There was no significant difference in respect of the operation time and bleeding of the experimental group compared with the control group. Conclusion The use of fentanyl-propofol compound in the operation of induced abortion can remarkably improve the tolerance of the pregnant women. It features effective analgesic effect, simple operation, and low side effects. It is safe and effective. Beside, it is required to strengthen the observation on respiration, circulation monitoring and analgesic during the nursing.